Doctors in central Wuhan are planning to conduct a long-term study of the effects of COVID-19 on the male reproductive system after a small study of 81 men revealed that coronavirus patients haed roughly half the normal ratio of testosterone after contracting the disease, according to SCMP.
Though still preliminary and not peer reviewed, the study is the first clinical observation of the potential impact of Covid-19, the disease caused by the coronavirus, on the male reproductive system, especially among younger groups.
In a paper published on the preprint research platform medRxiv.org, the researchers – from Zhongnan Hospital of Wuhan University and the Hubei Clinical Research Centre for Prenatal Diagnosis and Birth Health – said they analysed blood samples from 81 men aged 20 to 54 who tested positive for the coronavirus and were hospitalised in January.
The median age of the participants was 38 and roughly 90 per cent of them had only mild symptoms. The samples were collected in the last days of their stay in hospital. -SCMP
Previous studies have shown that coronavirus binds with the protein receptor cell, ACE2, a large number of which are found in the testicles.
Researchers looked at the ratio of testosterone to luteinising hormone (T/LH) - finding that the average ratio for COVID-19 patients was 0.74, around half the normal level. A low T/LH ratio can signal hypogonadism - a malfunction of the testicles which could lead to lower production of the sex hormone.
Testosterone is the main male sex hormone critical for the development of primary and secondary sexual characteristics including testes, muscle, bone mass and body hair. Luteinising hormone is found in both men and women, and best known for its ability to trigger ovulation. -SCMP
Those with hypogonadism can develop large breasts and erectile dysfunction - a condition which can be cured with testosterone treatment.
"Since more than half of the people with Covid-19 were reproductive-aged, more attention should be paid to the effect of Sars-CoV-2 on the reproductive system," the Wuhan researchers wrote - noting that their results were inconclusive and that other factors such as medication and immune system response could also trigger changes in hormones.
As such, the researchers say they plan a long-term study which may include the collection and analysis of sperm samples as well as interviews with coronavirus patients.
Professor of reproductive medicine at Tongji Hospital in Wuhan, Li Yufeng, had predicted in a study that the testicles could become a 'major target' in a coronavirus infection.
Other studies have also suggested that severe acute respiratory syndrome, or Sars, a distant relative of the new coronavirus, could also cause inflammation in the testicles.
A researcher with the State Key Laboratory of Reproductive Medicine at Nanjing Medical University, said the new observations were “highly valuable information” but a bigger sample would be needed to clarify the results. -SCMP
"Many viruses can affect fertility, but not every virus can cause a pandemic. If the impact is long lasting, it can be a problem," said the researcher - speaking on condition of anonymity.
Mainstream media telling men to freeze their sperm before receiving coronavirus vaccine
By Arsenio Toledo- 09. January 2021
Mainstream media outlets are telling men to strongly consider freezing their sperm before receiving a Wuhan coronavirus (COVID-19) vaccine because it can lead to future fertility problems.
This is according to the University of Miami, which is conducting research into the new coronavirus vaccines flooding the United States to ascertain whether or not they can cause infertility and whether they have any other damaging effects.
— Michelle Malkin (@michellemalkin) December 24, 2020
The study is being led by Dr. Ranjith Ramasamy, a reproductive urologist working for the University of Miami Health System and an expert in male infertility, andrology, sexual dysfunction and hypogonadism. He led an earlier study that found that the coronavirus was present in the testicles of men with COVID-19 for up to six months after the initial infection.
“We are evaluating the sperm parameters and quality before the vaccine and after the vaccine,” said Ramasamy. “From the biology of the COVID vaccine, we believe it shouldn’t affect fertility but we want to do the study to make sure that men who want to have kids in the future, to assure them it’s safe to go ahead and get the vaccine.”
While Ramasamy and his team’s initial hypothesis is that the coronavirus vaccine will not affect male fertility in any way, they want to have the data to back up their claim.
Ramasamy and his team are looking for men between the ages of 18 and 50 who are willing to go through a fertility evaluation before they receive the coronavirus vaccine.
“We want to see if there is any decrease in sperm production or quality,” said Dr. Daniel Nassau, a member of the research team and a urology fellow at the University of Miami Miller School of Medicine.
“We will look at a semen sample before they get the vaccine, and then at three and six months thereafter.”
Study participants are being strongly urged to freeze their sperm prior to vaccination to protect their fertility. (Related: Pfizer coronavirus vaccine warning: No breastfeeding or getting pregnant after being immunized it might damage the child.)
Mainstream media outlets have amplified Ramasamy’s call for men to freeze their sperm before taking the vaccine, including WPLG Local 10, the Miami affiliate of ABC, and WAVY-TV 10, the Portsmouth, Virginia-based local affiliate of NBC.
Prior University of Miami study found COVID-19 affects male fertility
Ramasamy and his team were able to discover that the virus isn’t limited to affecting the respiratory system, but can in fact also be debilitating to male fertility. Their previous study found that COVID-19 has the potential to cause male infertility and can possibly be spread sexually by asymptomatic men.
According to Dr. Robin Poe-Zeigler, the medical director of the New Hope Center for Reproductive Medicine in Virginia, research has found that the angiotensin-converting enzyme 2, or ACE2 “receptor,” a specific protein that allows the coronavirus to infect human cells, has been found in tissues around the body, including the lungs, the gastrointestinal tract, the liver and, more importantly, testicular tissue.
This means that the coronavirus can harm testicular tissue even if men with COVID-19 don’t show any symptoms. More research is being conducted to learn just how much of the virus is needed to be present in the testes before it can be detected in semen, and whether or not men can pass the coronavirus like a sexually transmitted disease.
“What they haven’t shown is [if] it actually infects the sperm cell, the actual sperm itself,” said Poe-Zeigler, who admitted that all they know for certain is that COVID-19 can infect testicular tissue. Studies have also failed to show that compromised fertility is long-lasting.
Poe-Zeigler, like mainstream media outlets, is warning men to consider freezing their sperm just in case.
“If we find there are long-lasting impacts, they will have at least one unaffected specimen that they could use for future conception efforts,” said Poe-Zeigler.
Unfortunately, Poe-Zeigler admitted that freezing the sperm isn’t a viable option for everyone because of the time and financial constraints that come with opting for artificial insemination or in vitro fertilization.
This makes the coronavirus vaccines very risky to take for men, especially those who are looking to start a family soon. Journalist Shane Trejo of alternative news website Big League Politics said that the vaccines “may end up causing worse health problems than the COVID-19 virus itself.”
“Big pharma will make out like bandits though so the truth will ultimately be swept under the rug by the globalists,” added Trejo. “The mass hysteria from the scamdemic is the perfect crisis to usher in a one-world technocracy.”
Learn more about the potentially harmful side effects that can come from receiving the coronavirus vaccine by reading the latest articles at Vaccines.news.
A new study has revealed that SARS-CoV-2, the virus which causes COVID-19, infects the testicles and likely impacts male fertility. Recall in March we reported that doctors in central Wuhan raised concerns over testicle damage after observing a lowered ratio of testosterone to luteinising hormone (T/LH).
Now, nine months later, a team of 14 researchers from Wuhan, China have published disturbing evidence from a small sample of patients that COVID-19 not only infects the testicles, but may interfere with sperm production by causing inflammation and 'massive' loss in young sperm cells.
The team's findings on how COVID-19 infects testicles corroborates the March reporting - namely, the SARS-CoV-2 spike protein binds to ACE2 receptors, which are produced throughout the body, including the seminiferous tubules which carry sperm while it matures.
"Strikingly, in four of the five cases, GC [germ cell] loss was massive, with only a few GCs left attached to the seminiferous tubules," reads the study, published Monday in Nature, Cellular & Molecular Immunology. Five COVID-19 patients included in the study were aged 51, 62, 70, 78 and 83 years of age, while control patients were 71, 78 and 80. And though they may lie on the older-end of the curve where male fertility has begun to decline, the control group's germ cells were "well aligned around the whole seminiferous tubules" compared to the COVID-19 patients.
"Consistent with the immunohistochemistry results, RT-qPCR showed significantly increased mRNA levels of ACE2 and TMPRSS2 in the testes of all COVID-19 patient compared to control patient testes," reads the report, which "further supports the hypothesis that SARS-CoV-2 is able to attack testicular cells." It is unknown how the virus increases ACE2 production in the testes.
"Collectively, our findings provide direct evidence that SARS-CoV-2 can infect the testis and GCs, indicating the potential impact of the COVID-19 pandemic on spermatogenesis and male fertility."
While the study is small with just five participants, the authors write that "further study is essential to reveal the underlying mechanism of SARS-CoV-2 infection of testicular cells and the correlation of testis infection with the clinical course of COVID-19."
Perhaps men who have recovered from COVID-19 should have their sperm counts tested?